斗牛棋牌

證照信息展示
合理用藥,關注健康
  1. 熱門藥品:
  2. 復方萬年青膠囊
  3. 萬全
  4. 米維
  5. 金戈
  6. 適今可
  7. 人血白蛋白
  8. 捷諾達
  9. 非布司他片

斗牛棋牌SHENGCHANCHANGJIA: NANJINGZHENGDATIANQINGZHIYAOYOUXIANGONGSI

PIZHUNWENHAO:GUOYAOZHUNZIH20120038

YAOPINGUIGE:0.5mg*7LI

YAOPINJIAGE:¥0YUAN

藥師來電

恩替卡韋膠囊的說明書

【TONGYONGMING】ENTIKAWEIJIAONANG

斗牛棋牌【CHENGFEN】GANZEZHUYAOCHENGFENWEI:ENTIKAWEIHUAXUEMINGCHENG:2-ANJI-9-[(1S,3R,4S)-4-QIANJI-3-QIANJIAJI-2-YAJIAJIHUANWUJI]-1,9-ERQING-6H-PIAOLING-6-TONGYISHUIHEWUFENZISHI:C12H15N5O3?H2OFENZILIANG:295.3

【XINGZHUANG】GANZEWEIJIAONANGJI,NEIRONGWUWEIBAISEHUOLEIBAISEXIAOWAN。

【SHIYINGZHENG】GANZESHIYONGYUBINGDUFUZHIHUOYUE,XUEQINGZHUANANMEIALTCHIXUSHENGGAOHUOGANZANGZUZHIXUEXIANSHIYOUHUODONGXINGBINGBIANDEMANXINGCHENGRENYIXINGGANYANDEZHILIAO。

【YONGFAYONGLIANG】HUANZHEYINGZAIYOUJINGYANDEYISHENGZHIDAOXIAFUYONGGANZE。TUIJIANJILIANG:CHENGRENHE16SUIJIYISHANGDEQINGSHAONIANKOUFUGANZE,MEITIANYICI,MEICI0.5mg。LAMIFUDINGZHILIAOSHIFASHENGBINGDUXUEZHENGHUOCHUXIANLAMIFUDINGNAIYAOTUBIANDEHUANZHEWEIMEITIANYICI,MEICI1mg(0.5mgLIANGLI)。GANZEYINGKONGFUFUYONG(CANQIANHUOCANHOUZHISHAO2XIAOSHI)。ZHILIAOQI:GUANYUGANZEDEZUIJIAZHILIAOSHIJIAN,YIJIYUCHANGQIDEZHILIAOJIEGUODEGUANXI,RUGANYINGHUA、GANAIDENG,MUQIANSHANGWEIMINGLE。

【藥理毒理】作用機制:甘澤為鳥嘌呤核苷類似物,對乙肝病毒(HBV)多聚酶具有抑制作用。它能夠通過磷酸化成為具有活性的三磷酸鹽,三磷酸鹽在細胞內的半衰期為15小時。通過與HBV多聚酶的天然底物三磷酸脫氧鳥嘌呤核苷競爭,恩替卡韋三磷酸鹽能抑制病毒多聚酶(逆轉錄酶)的所有三種活性:(1)HBV多聚酶的啟動;(2)前基因組mRNA逆轉錄負鏈的形成;(3)HBVDNA正鏈的合成。恩替卡韋三磷酸鹽對細胞的α、β、δDNA多聚酶和線粒體γDNA多聚酶抑制作用較弱,Ki值為18至大于160μM。抗病毒活性:在轉染了野生型乙肝病毒的人類HepG2細胞中,恩替卡韋抑制50%病毒DNA合成所需濃度(EC50)為0.004μM。恩替卡韋對拉米夫定耐藥病毒株(rtL180M,rtM204V)的EC50中位值是0.026μM(范圍0.01至0.059μM)。恩替卡韋與HIV核苷逆轉錄酶抑制劑(NRTIs)聯合給藥,不太可能降低恩替卡韋的抗HBV療效或后一類藥物中任何一種藥物的抗HIV療效。抗HIV病毒活性:全面分析恩替卡韋對一組實驗室分離毒株以及臨床分離的1型人類免疫缺陷病毒株(HIV-1)的抑制活性,在不同細胞及實驗條件下獲得的EC50值范圍是0.026到>10μM;當病毒水平降低時觀察到更低的EC50值。在細胞培養中,恩替卡韋在微摩爾濃度水平時可選擇出HIV逆轉錄酶的M184I位點置換,在恩替卡韋高濃度水平時證實了抑制作用。含M184V位點置換的HIV變異株對恩替卡韋失去敏感性。耐藥性:位于逆轉錄酶區有rtM204I/V和rtL180M位點置換的拉米夫定耐藥株(LVDr)對恩替卡韋的敏感性較HBV野毒株下降了8倍。合并額外恩替卡韋耐藥氨基酸斗牛棋牌rtT184,rtS202和/或rtM250位點改變的,在細胞培養還發現,對恩替卡韋的敏感性降低。合并額外(rtT184A,C,F,G,I,L,M或S;rtS202C,G或I;和/或rtM250I,L或V)位點置換的臨床分離株與野毒株相比,對恩替卡韋的敏感性進一步降低了16至741倍。單獨出現rtT184,rtS202和rtM250恩替卡韋耐藥位點置換的病毒株對恩替卡韋的敏感性僅有適度影響,在超過1000例沒有拉米夫定耐藥位點置換的患者中未觀察到敏感性降低。細胞培養中發現,耐藥性是通過改變HBV逆轉錄酶減少競爭結合而介導的,耐藥的HBV毒株復制能力減弱。臨床研究:臨床研究中對初始接受恩替卡韋0.5mg(核苷初治)或1mg(拉米夫定失效)治療,并且在治療24周或之后有治療中的HBVDNAPCR檢測值的患者均進行耐藥監測。核苷類藥物初治患者:核苷類藥物初治患者研究中恩替卡韋長達144周治療發現有rtT184、rt202和/或rtM250恩替卡韋耐藥位點置換基因檢測證據的患者比例

【YAODAIDONGLIXUE】XISHOU:JIANKANGSHOUSHIZHEKOUFUYONGYAOHOU,GANZEBEIXUNSUXISHOU,0.5DAO1.5XIAOSHIDADAOFENGNONGDU(Cmax)。MEITIANGEIYAOYICI,6—10TIANHOUKEDAWENTAI,LEIJILIANGYUEWEILIANGBEI。SHIWUDUIKOUFUXISHOUDEYINGXIANG:JINSHIBIAOZHUNGAOZHICANHUODIZHICANDETONGSHIKOUFU0.5mgGANZEHUIDAOZHIYAOWUXISHOUDEQINGWEIYANCHI(CONGYUANLAIDE0.75XIAOSHIBIANWEI1.0—1.5XIAOSHI),CmaxJIANGDI44—46%,YAOSHIQUXIANXIAMIANJI(AUC)JIANGDI18—20%。YINCI,GANZEYINGKONGFUFUYONG(CANQIANHUOCANHOUZHISHAO2XIAOSHI)。FENBU:YAODAIDONGLIXUEZILIAOBIAOMING,QIBIAOGUANFENBURONGJICHAOGUOQUANSHENYETILIANG,ZHESHUOMINGGANZEGUANGFANFENBUYUGEZUZHI。TIWAISHIYANBIAOMINGGANZEYURENXUEJIANGDANBAIJIEHELVWEI13%。DAIXIEHEQINGCHU:ZAIGEIRENHEDASHUFUYONG14CBIAOJIDEENTIKAWEIHOU,WEIGUANCHADAOGANZEDEYANGHUAHUOYIXIANHUADAIXIEWU,DANGUANCHADAOSHAOLIANGIIQIDAIXIECHANWUPUTAOTANGQUANSUANDAIJIEHEWUHELIUSUANJIEHEWU。ENTIKAWEIBUSHIXIBAOSESUP450(CYP450)MEIXITONGDEDIWU、YIZHIJIHUOYOUDAOJI。ZAIDADAOXUEJIANGFENGNONGDUHOU,XUEYAONONGDUYISHUANGZHISHUFANGSHIXIAJIANG,DADAOZHONGMOQINGCHUBANSHUAIQIYUEXU128—149XIAOSHI。YAOWULEIJIZHISHUYUEWEIMEITIANYICIGEIYAOJILIANGDE2BEI,ZHEBIAOMINGQIYOUXIAOLEIJIBANSHUAIQIYUEWEI24XIAOSHI。GANZEZHUYAOYIYUANXINGTONGGUOSHENZANGQINGCHU,QINGCHULVWEIGEIYAOLIANGDE62—73%。SHENQINGCHULVWEI360—471mL/min,QIEBUYILAIYUGEIYAOJILIANG,ZHEBIAOMINGENTIKAWEITONGSHITONGGUOSHENXIAOQIULVGUOHEWANGZHUANGXIAOGUANFENMI。

【BULIANGFANYING】ZAIGUOWAIJINXINGDEYANJIUZHONG,GANZEZUICHANGJIANDEBULIANGSHIJIANYOU:TOUTONG、PILAO、XUANYUN、EXIN。LAMIFUDINGZHILIAODEHUANZHEPUBIANCHUXIANDEBULIANGSHIJIANYOU:TOUTONG、PILAO、XUANYUN。ZAIZHE4XIANGYANJIUZHONG,FENBIEYOU1%DEENTIKAWEIZHILIAODEHUANZHEHE4%LAMIFUDINGZHILIAODEHUANZHEYOUYUBULIANGSHIJIANHESHIYANSHIJIANCEZHIBIAOYICHANGERTUICHUYANJIU。ZAIZHEXIEYANJIUZHONG,SHIYONGENTIKAWEIDEHUANZHEZAIZHILIAOGUOCHENGZHONGFASHENGALTZENGGAOZHI10BEIDEZHENGCHANGZHISHANGXIANHEJIXIANZHIDE2BEISHI,TONGCHANGJIXUYONGYAOYIDUANSHIJIAN,ALTKEHUIFUZHENGCHANG;ZAICIZHIQIANHUOTONGSHIBANSUIYOUBINGDUZAILIANG2GEDUISHUZHIDEXIAJIANG。GUZAIYONGYAOQIJIAN,XUDINGQIJIANCEGANGONGNENG。TINGZHIZHILIAOHOUDEGANYANJIAJU:GANYANJIXINGJIAJUHUOALTFURANDEDINGYIWEI:ALTDAYU10BEIDEZHENGCHANGZHISHANGXIANHEDAYU2BEIHUANZHEDECANKAOSHUIPING(JIXIANZHIHUOTINGYAOSHIZUIHOUYICIJIANCEZHIJIANDEZUIXIAOZHI)。ZHEXIEYANJIUZHONG,RUGUOZAIDI52ZHOUHUOZHIHOUDADAOFANGANSUOGUIDINGDEZHILIAOYINGDAHOU,KEYUNXUYIYAZUHUANZHETINGYAO。RUGUOWEIDADAOZHILIAOYINGDAERTINGYONGENTIKAWEI,ZETINGYAOHOUFASHENGALTFURANDEGAILVKENENGGENGGAO。TINGYAOHOUEHUADEZHONGWEISHIJIANDUIYUENTIKAWEIZHILIAODEHUANZHEWEI23ZHOU,ERDUIYULAMIFUDINGZHILIAODEHUANZHEWEI10ZHOU。ZAIZHONGGUOJINXINGDELINCHUANGSHIYANZHONG,ZUICHANGJIANDEBULIANGSHIJIANYOU:ALTSHENGGAO、PILAO、XUANYUN、EXIN、FUTONG、FUBUBUSHI、SHANGFUTONG、GANQUBUSHI、JITONG、SHIMIANHEFENGZHEN。ZHEXIEBULIANGSHIJIANDUOWEIQINGDAOZHONGDU。ZAIYULAMIFUDINGDUIZHAODESHIYANZHONG,GANZEBULIANGSHIJIANDEFASHENGLVYULAMIFUDINGXIANGDANG。

斗牛棋牌【ZHUYISHIXIANG】SHENGONGNENGBUQUANDEHUANZHE:JIGANQINGCHULV

斗牛棋牌【JINJI】DUIENTIKAWEIHUOZHIJIZHONGRENHECHENGFENGUOMINZHEJINYONG。

【ZHUZANG】MIFENG,25℃YIXIAGANZAOCHUBAOCUN。

【YOUXIAOQI】24GEYUE。

【SHENGCHANCHANGJIA】NANJINGZHENGDATIANQINGZHIYAOYOUXIANGONGSI

恩替卡韋膠囊的功效與作用

斗牛棋牌ENTIKAWEIJIAONANGENTIKAWEIJIAONANGJUYOUGANZESHIYONGYUBINGDUFUZHIHUOYUE,XUEQINGZHUANANMEIALTCHIXUSHENGGAOHUOGANZANGZUZHIXUEXIANSHIYOUHUODONGXINGBINGBIANDEMANXINGCHENGRENYIXINGGANYANDEZHILIAO。BAOZHILINDAYAOFANGENTIKAWEIJIAONANGYEMIANTIGONGNANJINGZHENGDATIANQINGZHIYAOYOUXIANGONGSISHENGCHANDEENTIKAWEIJIAONANG,ENTIKAWEIJIAONANGSHUOMINGSHUHANENTIKAWEIJIAONANGJIAGE、ENTIKAWEIJIAONANGDEGONGXIAOYUZUOYONG、ENTIKAWEIJIAONANGDEYONGFAYONGLIANG、ENTIKAWEIJIAONANGDEFUZUOYONGYUBULIANGFANYING、ENTIKAWEIJIAONANGDEZHUYISHIXIANGYUJINJIDENGXINXI。

  • 腫瘤用藥
  • 肝膽用藥
  • 神經精神
  • 免疫用藥
  • 胃腸用藥
  • 心腦血管
  • 風濕骨病
  • 泌尿用藥

恩替卡韋膠囊的同類產品

新癀片
規格:0.32g*9片*2板
阿德福韋酯片
規格:10mg*14片
恩替卡韋膠囊
規格:0.5mg*7粒
苦參素片
規格:0.1g*24片
秘訣清涼膠囊
規格:0.4g*40粒
恩替卡韋分散片
規格:0.5mg*7片

營業執照信息 | 藥品經營許可證 | GSP認證證書 | 互聯網藥品信息服務資格證書 | 醫療器械經營許可證 | 食品經營許可證

HULIANWANGYAOPINXINXIZIGEZHENG: (YUE)--FEIJINGYINGXING--2015--0157 | YUEICPBEI13051054HAO

斗牛棋牌?2013-2020 GUANGZHOUSHIBAOZHILINYAOYEYOUXIANGONGSI BANQUANSUOYOU

斗牛棋牌FALVGUWEN:GUANGDONGZHENGDALIANHELVSHISHIWUSUO TEBIESHENGMING:BENZHANNEIRONGJINGONGCANKAO,BUZUOWEIZHENDUANJIYILIAOYIJU。

  1. 官方微信
  2. 手機商城

GUANZHUWEIXIN

WEIXINYAOSHI

YONGYAOZIXUN

DIANHUAZIXUN

Q QZIXUN

TOP

BAOZHILINDAYAOFANG

藥監認證
正品保證

訂購熱線:4001-020-870

稍后咨詢